The sides met less than two months ago in the Africa Cup of Nations Final in Cameroon, and it was Senegal who came out on top that day as they won on penalties following a goalless draw.
Their attention now turns to a two-legged tie for a World Cup spot in Qatar, with Egypt having home advantage in the first leg. Liverpool duo Mohamed Salah and Sadio Mane will once again take much of the focus.
Here’s all you need to know about tonight’s first-leg clash...
Date, kick-off time and venue
Egypt vs Senegal is scheduled for a 7:30pm GMT kick-off tonight, Friday March 25, 2022.
The Cairo International Stadium in Egypt will host the match.
Where to watch Egypt vs Senegal
TV channel: Tonight’s match is not being broadcast live on TV in the UK.
Live stream: Fans can watch the action via streaming service Mola TV. Users have to register, but it is free to watch
Live coverage: You can also follow updates from the game with Standard Sport’s dedicated live blog.
Egypt vs Senegal team news
Egypt general manager Diaa El-Sayed confirmed that Salah will be available for the Senegal qualifier.
He said: “Salah is fit and ready for the clash.”
Seny Dieng and Alfred Gomis miss out on the Senegal squad to injury, but it’s still a star-studded group available.
Mane, Edouard Mendy and Ismaila Sarr are among the Premier League players ready to help their country book a place in Qatar.
Egypt squad
Goalkeepers: Mohamed El-Shennawy, Mohamed Abou-Gabal, Mohamed Sobhi
Defenders: Yasser Ibrahim, Mohamed Abdelmomen, Ayman Ashraf, Omar Kamal, Omar Gaber, Mahmoud Hamdy El-Wensh, Mahmoud Alaa, Ahmed Fatouh
Midfielders: Hamdi Fathi, Amr El-Sulya, Mohamed Magdy Afsha, Mohamed Elneny, Nabil Emad Dunga, Emam Ashour
Forwards: Mohamed Salah, Omar Marmoush, Mahmoud Hassan Trezeguet, Mostafa Mohamed, Marwan Hamdi, Ahmed Sayed Zizo
Senegal squad
Goalkeepers: Edouard Mendy, Alioune Badara Faty, Bingourou Camara
Defenders: Bouna Sarr, Kalidou Koulibaly, Abdou Diallo, Saliou Ciss, Pape Abou Cisse, Fode-Ballo Toure, Youssouf Sabaly, Abdoulaye Seck
Midfielders: Idrissa Gana Gueye, Nampalys Mendy, Cheikhou Kouyate, Pape Matar Sarr, Moustapha Name, Loum Ndiaye, Pape Gueye
Forwards: Sadio Mane, Ismaila Sarr, Famara Diedhiou, Bamba Dieng, Keita Balde Diao, Habib Diallo, Mame Baba Thiam, Boulaye Dia
Egypt vs Senegal prediction
Games between these two sides are not exactly known for producing a huge amount of goals. In 13 meetings between them, only once have there been more than two scored.
First-leg matches are often nervy and tight anyway, but Senegal might just sneak what would be a crucial win away from home to take back for the return fixture.
Senegal win, 1-0.
Head to head (h2h) history and results
Egypt wins: 6
Draws: 2
Senegal wins: 5
